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People with Ehlers-Danlos syndrome (EDS) or Hypermobility Spectrum Disorder (HSD) often live with headaches, dizziness, fatigue, or brain fog that seem unrelated. An overlooked factor may be craniocervical instability (CCI) — looseness in the ligaments where the skull meets the spine. In connective-tissue disorders, this instability can irritate the brainstem, disrupt blood flow, and mimic other conditions like migraine, fibromyalgia or ADHD-like symptoms.